Pancuronium Dibromide

Code: 5052260001 D2-231

Biochem/physiol Actions

Primary TargetnAChR

General description

A highly potent competitive antagonist selective for nAChRs (IC50 = 5....


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€73.50 EACH
€90.41 inc. VAT

Biochem/physiol Actions

Primary TargetnAChR

General description

A highly potent competitive antagonist selective for nAChRs (IC50 = 5.5 nM). A very potent non-depolarizing skeletal muscle relaxant but no sedative or analgesic effects.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Lowenick et al., 2001. Eur. J. Pharmacol.413, 31.r>Melnikov, L., et al., 1999. Gen Pharmacol.33, 313.r>Maestrone, E., et al., 1994. Br. J. Pharmacol.111, 283.r>Fryer, D., et al., 1987. Naunyn Schmiedebergs Arch. Pharmacol.335, 367.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Warning

Toxicity: Toxic (F)

assay≥98% (NMR)
coloroff-white
formsolid
InChI keyNPIJXCQZLFKBMV-YTGGZNJNSA-L
InChI1S/C35H60N2O4.2BrH/c1-24(38)40-32-21-26-13-14-27-28(35(26,4)23-31(32)37(6)19-11-8-12-20-37)15-16-34(3)29(27)22-30(33(34)41-25(2)39)36(5)17-9-7-10-18-36;;/h26-33H,7-23H2,1-6H3;2*1H/q+2;;/p-2/t26-,27+,28-,29-,30-,31-,32-,33-,34-,35-;;/m0../s1
manufacturer/tradenameCalbiochem®
potency5.5 nM IC50
Quality Level100
solubilitywater: 100 mM
storage conditionprotect from light, OK to freeze
storage temp.2-8°C
Cas Number15500-66-0
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